LAB ONE N°1 BUTYRIC ACID 60 capsules

The dietary supplement LAB ONE N°1 Butyric ACID 60 capsules is a product based on sodium butyrate, or sodium salt, an organic compound containing a residue of butyric acid. Its chemical name is butyric acid.

Butyric acid is formed in the large intestine during the fermentation of sugars by bacteria of the genera Clostridium spp, Eubacterium spp, Fusobacterium spp, etc. The richest sources of butyric acid in the large intestine are resistant starch, oats, and wheat bran. [1]

Butyric acid provides energy to enterocytes, the normal cells of the intestinal epithelium. Unfortunately, it is supplied by the diet in too small amounts to fulfill this function.

Furthermore, this acid helps reduce the severity of diarrheal symptoms of various origins. Additionally, it contributes to the restoration of the structural and functional integrity of the intestines and influences the normal motility of the digestive tract. Butyric acid increases the absorption of sodium and thus water in the intestine. It also has an effect on normalizing the bacterial flora.

It is interesting to note that butyric acid also accelerates the regeneration of damaged intestinal epithelial cells and has an anti-inflammatory effect with a reduction of pro-inflammatory cytokines (IL-6, IL-8, TNF-α) and protects against the leakage of bacteria from the intestine into the bloodstream.

A deficiency of butyric acid in the gastrointestinal tract can lead to mucosal dysfunction in the small and large intestines. Insufficient concentrations of butyric acid in the intestinal lumen cause energy deficiencies in colonocytes and, consequently, impaired epithelial regeneration and maintenance of epithelial integrity[2]. [2]

In conclusion, the dietary supplement LAB ONE N°1 BUTYRIC ACID 60 capsules is a product of simple composition in the form of convenient capsules, which provides butyric acid in the form of sodium butyrate, which increases its bioavailability.

1 Kotunia, A., Pietrzak, P., Guilloteau, P., & Zabielski, R. (2010). Butyric acid in the gastrointestinal tract.Prz Gastroenterol, 5, 117-22.

2 Banasiewicz, T., Borycka-Kiciak, K., Dobrowolska-Zachwieja, A., Friediger, J., Kiciak, A., Krokowicz, P., ... & Zabielski, R. (2010). Clinical aspects of the use of butyric acid in the dietary management of intestinal diseases .Review of Gastroenterology 2010 ; 5 : 329, 334.

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